Course Description

Week 1          Preformulation I

Preformulation I: Physical form (crystal & amorphous), 

Preformulation I: polymorphism, particle size, shape

Preformulation I:, solubility profile (pKa, pH)

Preformulation I: Partition coefficient, flow properties

Week 2          Preformulation II

Preformulation II: Hydrolysis, oxidation, reduction

Preformulation II: Racemisation, 

Preformulation II: Dissolution, permeability & BCS classification

Preformulation II: Polymerization

Week 3          Tablets

Tablets: Introduction, classification of tablets. Formulation/preparing of tablets, granulation methods.

Tablets: Compression and processing problems. Equipment and tablet tooling, Tablet defects.

Tablets: Tablet coating: Types, coating materials, formulation of coating composition, methods of coating, equipments employed and defects in coating

Tablets: QC of tablets: apparatus, methods, graphical presentations, official and unofficial tests.

Week 4          Liquid Orals

Liquid orals: Formulation and manufacturing of solution, syrups and elixirs, Filling and packaging

Liquid orals: Emulsions: I

Liquid orals: Emulsion II

Liquid orals: Suspensions: Formulation, evaluation

Week 5          Parenterals I

Parenterals I: Introduction, Preformulation of parenterals

Parenterals I: Formulation of Parenterals

Week 6          Parenterals I

Parenterals I: Types of Parenteral preparation

Parenterals I: Lay out and Production facilities

Week 7          Parenterals II

Parenterals II: Pyrogens and pyrogenisity

Parenterals II: Quality control of parenterals

Week 8          Capsules

Capsules: Introduction, Advantages, Disadvantages, Capsule Production, hard Gelatin capsules

Capsules: Methods of filling capsules, Soft Gelatin Capsules

Capsules: Formulation Consideration, Production of soft gelatin capsules, Non-gelatin soft capsules

Capsules: Evaluation of commercial capsules

Week 9          Pellets and Ophthalmic Preparations

Pellets: Introduction, formulation, pelletization process, equipment needed

Ophthalmic Preparations: Introduction, absorption through eye, formulation considerations

Ophthalmic Preparations:  formulation of eye drops, lotion, ointments

Ophthalmic Preparations:  Methods of preparation; labeling, containers Evaluation

Week 10        Pharmaceutical Aerosols

Pharmaceutical Aerosols: Definitions, Advantages, Limitation, Uses

Pharmaceutical Aerosols: Components of aerosols

Pharmaceutical Aerosols: Components and systems of aerosols

Pharmaceutical Aerosols: inhalers and  Evaluation of Aerosols

Week 11        Cosmetics

Cosmetics: Introduction, absorption through skin, types of cosmetic preparations, Formulation of tooth pastesCosmetics: Formulation of lipsticks, shampoos, hair dyes  

Cosmetics: Formulation of cold cream and vanishing cream, sunscreens

Week 12        Packaging Materials Science

Packaging Materials Science: Materials used for packaging of pharmaceutical products, 

Packaging Materials Science: Factors influencing choice of containers Legal and official requirements, Stability aspects,

Packaging Materials Science: Quality control tests of packaging materials